Study to assess the effectiveness of laparoscopic removal of peritoneal endometriosis for the management of chronic pelvic pain

If you are a woman undergoing a diagnostic laparoscopy for the investigation of chronic pelvic pain and have not previously had endometriosis diagnosed during surgery you may be able to help with the ESPriT1 study.

Researchers within four Scottish NHS Health Boards are recruiting women with chronic pelvic pain and suspected endometriosis to this feasibility study. The results of the study will be used to design a larger multi-centre clinical trial looking at whether surgical removal of peritoneal endometriosis improves pelvic pain and quality of life.

Why is this study needed?

At the moment, there is no strong evidence that surgery to remove (isolated) peritoneal endometriosis improves painful symptoms and quality of life. This feasibility study will help us design a larger study to help answer this question.

To take part in this study you need to be:

  • A patient within NHS Lothian, NHS Grampian, NHS Tayside, or NHS Greater Glasgow and Clyde
  • Aged 18 to 55
  • Undergoing a laparoscopy for suspected endometriosis (and have no previous surgical diagnosis of endometriosis)

What does the study involve?

  • If only peritoneal endometriosis is found during your diagnostic laparoscopy, you will be randomly allocated to one of two groups. One group will receive a diagnosis and have the endometriosis removed, while the other group will receive a diagnosis only. Both groups will have access to available hormonal and painkiller medications.
  • You will be asked to complete pain, symptom, and quality of life questionnaires before and after the surgery.

By taking part in this study you will be helping us move closer to finding out whether or not surgical management of peritoneal endometriosis improves women’s pain and quality of life.

How to get involved

If you would like to find out more about the ESPriT1 study please contact your local research team (details below) or email us.

Aberdeen: Danielle Pirie | 01224 438306 | Email

Dundee: Caroline Tee | 01382 632287 ext 32287 | Email

Edinburgh: Nicola Watson | 0131 242 7904 | Email

Glasgow: Reproductive Health Team | 0141 232 7600 | Email

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