Endometriosis: Science and practice

Edited by Linda C Giudice, Johannes LH Evers, and David L Healy

Endometriosis: Science and practice must be described as the definitive and all inclusive book on endometriosis.  It provides a comprehensive approach to the biology, diagnosis, and treatment of endometriosis, showcasing the latest in molecular, genetic, and epigenetic research underlying the pathophysiology of endometriosis.

It is a must read for every single person who is serious about moving the field of endometriosis forward.

Expertly edited by professors Linda Giudice, Johannes Evers, and David Healy, the book provides a complete overview of the knowledge gathered from the increased understanding of endometriosis over the past 20 years.

This is the first time such a complete compilation has been published on endometriosis addressing not only basic research, diagnosis, and therapeutics, but also treatment outcomes and impact.

One-hundred-and-fourteen leading (and actively practising) surgeons, physicians, researchers, as well as emerging leaders in the field of endometriosis, have contributed with their insights into this complex disease providing very short links between the laboratory and clinical practice.

The ten sections of this 600-page book comprise:

1. History, epidemiology, and economics
2. Pathogenesis
3. Disease characterisation and classification
4. Biological basis and pathophysiology of endometriosis, including early origins of endometriosis, stem cells, angiogenesis, genetics, steroid hormones, inflammation, neuroendocrine aspects, and the mechanisms involved in pain and infertility
5. Models of endometriosis, including in vivo, in vitro, and animal models
6. Diagnosis of endometriosis, including surgical, biomarkers, imaging, proteomics, and transcriptomics
7. Medical therapies for pain
8. Surgical therapies for pain
9. Infertility and endometriosis
10. Associated disorders, including cancer, autoimmunity, and psychosomatic and compromised sexuality aspects.

The book concludes with an “eye to the future” in terms of emerging research, diagnostics, and therapeutics.

We hope that learners of all ages and from multiple disciplines, clinicians, researchers, and patients will benefit from the knowledge imparted in the pages of this book, which we hope will stimulate new knowledge, so one day we can cure endometriosis or, perhaps, even better, prevent it.

said the three editors.