Clinical trials in endometriosis

Feeling the pain caused by endometriosis? You may qualify for a new medical research study in the United States

If you’re a woman age 18 to 49 and have been diagnosed with endometriosis, you’re invited to see if you may qualify for the Lilac Petal Study.

The purpose of the research study is to evaluate the safety and effectiveness of an investigational medication for the management of pelvic pain associated with endometriosis. Physicians in your area are currently conducting the study.

Qualified participants will receive investigational study medication, study-related medical exams, and lab tests at no charge. Financial compensation for time and travel may also be available. To learn more, visit www.LilacPetalStudy.com or call 1-866-PETAL-01 (1-866-738-2501).

Clinical study to test the effectiveness of interferential stimulation in maintaining bone mineral density while taking a GnRH agonist (Zoladex)

Have you been prescribed a GnRH agonist for 6 months for endometriosis or any other reason?

If so, would you be interested in taking part in a research study at the University of Oxford, United Kingdom?

We are trying to find out if using a device like a TENS machine (which delivers mild electrical stimulation to the back) can prevent the small amount of bone loss which typically occurs with this type of drug. These temporary changes in bone density mimic those that occur around the time of menopause. Electrical stimulation may be a safe way to reduce or eliminate loss of bone density.

Further information about the study can be obtained by downloading the Patient Information Sheet [PDF]

If you are interested in particpating, please contact:
Fenella Roseman
Telephone: (+44) 01865 221003
Fenella.Roseman@obs-gyn.ox.ac.uk

Clinical trial for the treatment of pain with endometriosis

We are currently enrolling for an endometriosis clinical research study for the treatment of pain. This study is a phase II, placebo-controlled, randomized, double-blind, multi-center study in which women will be given once daily capsules for four months and then followed for six months post-treatment. Pharmacokinetic blood sampling will be performed at day 0 and at the end of each monthly interval, during the four month treatment phase. The study length is approximately 1 year.

More information can be found at www.clinicaltrials.gov.

Inclusion criteria

• Premenopausal women aged 18-48 inclusive
• Endometriosis documented by laparoscopic or surgical assessment within the past ten (10) years
• Clinical symptoms of endometriosis for at least the past three (3) months
• Endometriosis symptoms
• Must be sexually active unless sexually inactive for endometriosis-related dyspareunia
• Must have a regular or steady menstrual cycle lasting from 24 to 36 days
• Other inclusion criteria may apply

Locations (United States only)

Alabama

Medical Affiliated Research Center
Huntsville, Alabama, United States, 35801
Contact: Joyce Todd 256-533-6603 jgm@marc-research.com
Principal Investigator: Anne Marie Reidy, MD

Arizona

Advanced Clinical Therapeutics, LLC
Tucson, Arizona, United States, 85712
Contact: Joanie Seibold 520-323-9601 jseibold@advancedtherapies.com
Principal Investigator: Walter Patton, MD

Arkansas

Lynn Institute of the Ozarks
Little Rock, Arkansas, United States, 72205
Contact: Holly Jarrell 501-975-2000 hjarrell@lhsi.net
Principal Investigator: Caroline May, MD

Florida

Comprehensive Clinical Trials
West Palm Beach, Florida, United States, 33409
Contact: Virginia Piechocniski 561-478-3177 regulatory@cctllc.net
Principal Investigator: Ronald Ackerman, MD

Altus Research
Lake Worth, Florida, United States, 33461
Contact: Cynthia Abath 561-296-7397 cindyabath@aol.com
Principal Investigator: Samuel Lederman, MD

Advanced Research Institute
New Port Richey, Florida, United States, 34655
Contact: Susan Randall 727-835-3261 srandallari@yahoo.com
Principal Investigator: Hugo Perez, MD

Illinois

Women's Health Practice, LLC
Champaign, Illinois, United States, 61820
Contact: Felisa Daniels 217-693-4413 felisa.daniels@womenshealthpractice.com
Principal Investigator: Suzanne Trupin, MD

Iowa

Medical Associates
Dubuque, Iowa, United States, 52002
Contact: Maureen Runde 563-584-4139 mmrunde@mahealthcare.com Principal Investigator: Trupti Mehta, MD

Massachusetts

East Coast Clinical Research, Inc
Haverhill, Massachusetts, United States, 01830-6141
Contact: Terry Stubbs 978-372-7252 tstubbs@eccresearch.com
Principal Investigator: Byungyol Chun, MD

New Jersey

Women's Health Research Center, LLC
Lawrenceville, New Jersey, United States, 08648
Contact: Cielito Mariani 609-896-0777 ext 239 cielitom_delval@comcast.net
Principal Investigator: Scott Eder, MD

North Carolina

Wake Research Associates
Raleigh, North Carolina, United States, 27612
Contact: Marsha Peery 919-781-2514 mpeery@wakeresearch.com
Principal Investigator: Pouru Bhiwandiwalla, MD

Physicians for Women
Cary, North Carolina, United States, 27511
Principal Investigator: Geoff Seidel, MD

Ohio

HWC Women's Research Center
Miamisburg, Ohio, United States, 45342
Contact: Angela Shields 937-866-1187 ashields@hwcwrc.com
Principal Investigator: James Huey, MD

Rapid Medical Research, Inc.
Cleveland, Ohio, United States, 44122
Contact: Clauida Lanesa 216-539-8384 claudia@rapidmedicalresearch.com
Principal Investigator: Mira Baron, MD

South Carolina

SC Clinical Research Center, LLC
Columbia, South Carolina, United States, 29201
Contact: Margaret Holt 803-988-1438 pholt@scclinicalresearch.com
Principal Investigator: Myles Davis, MD

Texas

Advanced Research Associates
Corpus Christi, Texas, United States, 78414
Contact: Bonnie Gutierrez 361-906-1277 ext 104 bonnie@araresearch.com
Principal Investigator: Charles Eubank, MD

Clinical Trials of Texas/Seven Oaks Women's Center
San Antonio, Texas, United States, 78229
Contact: Mary Jo Perez-Jenkins 210-949-0122 mjenkins@cttexas.com Principal Investigator: Brian Harle, MD

Clinical Trials of Texas/Institute for Women's Health
San Antonio, Texas, United States, 78229
Contact: Kate Blair 210-949-0122 kblair@cttexas.com
Principal Investigator: Jose Ruiz, MD

Utah

Wasatch Clincal Research
Salt Lake City, Utah, United States, 84107
Contact: Karen George 801-288-0607 kgeorge@wasatchcrc.com
Principal Investigator: Steven Thackeray, MD

Clinical Study for the Treatment of Moderate-to-Severe Pain Associated with Endometriosis

If you suffer from pain because of your endometriosis, you may qualify to participate in a research study testing the safety and effectiveness of an FDA approved drug given in a different form.

This study is currently taking place only in the United States and participation will last approximately 4 months and will require approximately 6 visits to the doctor’s office

The following are requirements to be considered for the study:

Be a menstruating female between the ages of 18-50.
Have a regular menstrual cycle length of 21 to 35 days with menstrual bleeding that typically lasts no more than 7 days.
Have moderate to severe pain associated with your endometriosis (the study doctor can help determine this).
Have had surgical or laparoscopic confirmation of your endometriosis no more than 60 months ago.
Have a negative pregnancy test and agree to use 2 forms of contraception throughout the study (condoms, spermicide, diaphragm, tubal ligation or vasectomy).
Discontinue the use of any intravaginal devices (Intrauterine devices, douches) during the study; use of tampons and diaphragms will be allowed during the study.
Be in good general health.
Be physically able and willing to follow the study schedule and daily diary requirements.

In order to participate in the study, you must not:

Be pregnant or nursing, or have a history of pregnancy within 6 months prior to study entry.
Have had a hysterectomy or planning to have a hysterectomy during the study.
Have any condition other than endometriosis that would require chronic use of pain medication.
Have received treatment with Danocrine® (oral danazol), Depo Provera®, or Lupron® within 6 months prior to study entry.
Have a known history of cancer of the breast or genital organs.
Have had major abdominal surgery that was not related to endometriosis within 6 months prior to study entry.
Have a history of or an active outbreak of genital or cervical herpes.
Have participated in a clinical investigation within 30 days prior to screening.
Have uncontrolled high blood pressure.

For more information and to participate:

TO FIND OUT MORE ABOUT THE STUDY AND LOCATE A PARTICIPATING PHYSICIAN, PLEASE REFER TO THE BELOW LISTINGS AND CONTACT THEIR OFFICE DIRECTLY TO TALK TO THE STUDY NURSE ABOUT THE STUDY AND IF YOU MAY QUALIFY.

IF YOU QUALIFY, YOU MAY RECEIVE: STUDY-RELATED MEDICATION, STUDY-RELATED LAB TESTS, STUDY-RELATED EXAMS AND COMPENSATION FOR YOUR TIME AND TRAVEL.

CITY, STATE	PHONE NUMBER	CONTACT PERSON
Little Rock, AR Chandler, AZ Phoenix, AZ San Diego, CA Denver, CO New Britain, CT Boynton Beach, FL Clearwater, FL Tampa, FL Alpharetta, GA Boise, ID Champaign, IL St. Louis, MO Winston-Salem, NC Bismarck, ND Fargo, ND Moorestown, NJ Cleveland, OH West Chester, PA Irving, TX Decatur, GA Salt Lake City, UT Baton Rouge, LA Columbus, OH	501-664-4131 480-732-7405 602-249-3050 858-505-8672 303-321-2255 888-434-2238 x 2057 561-964-7880 727-724-9730 813-739-1174 770-475-1395 208-947-9805 217-356-3736 314-692-8013 x 2012 336-760-3909 888-788-3936 701-232-2388 856-235-4341 888-460-2275 610-840-1500 214-367-8400 404-534-9359 801-288-0607 225-757-1084 614-882-4343	Allison Overton Stephanie Courtney Jenat Donnis Moore Gina Panek Zoe Argain Bonnie Silvers Amayvis Rebolledo Kathie Bernstein Amanda Cambra Jaime Thompson Jennifer Crocker Patricia Creed Call Center Angela Barbara Brown Lynn Tucker Michelle Murphy Jai Fields Tanyece Edwards Wasatch Clinical Research Leslie Turner Sheila E. Brooks

Please contact us if you wish to announce a clinical trial