Research and treatments

Latest news on clinical and scientific research in endometriosis.


Review of effectiveness of LUNA and PSN in endometriosis surgery
31 May 2007

31 May 2007 Systematic review of laparoscopic uterosacral nerve ablation (LUNA) and presacral neurectomy (PSN) shows the evidence for nerve interruption in the management of dysmenorrhea is limited A review lead by Latthe et al at the University of Birmingham, UK, aimed to compare the two main surgical procedures available designed to cut sensory nerves […]

Statins show promise for relief of endometriosis
5 March 2007

5 March 2007 Canadian study shows that women suffering from endometriosis may benefit from statin treatment due to its inhibitory effect on angiogenesis. Robert Casper and his team, from the Toronto Centre for Advanced Reproductive Technology, set out to investigate the inhibitory effect of a statin on angiogenesis in a three-dimensional (3-D) culture of human […]

Diagnostic delay in endometriosis is confirmed – but why?
15 February 2007

Karen Ballard’s study describes women’s experiences of reaching a diagnosis of endometriosis. The authors call for more awareness of endometriosis to reduce an 8.5 year diagnostic delay.

STAT6 gene implicated in endometriosis
15 January 2007

January 2007 Indian scientists have identified the STAT6 gene G2964A 3′-UTR polymorphism as possibly increasing women’s risk of developing endometriosis. Researchers in Southern India hypothesised that a common G2964A single-nucleotide polymorphism (SNP) in the 3′-untranslated region (UTR) of the STAT6 gene, known to be associated with common immunological diseases such as asthma and Crohn’s disease, […]

Progesterone receptor gene alleles linked with endometriosis risk
15 January 2007

January 2007 Women who carry the progesterone receptor (PR) gene allele +331A appear to have a reduced risk for deep infiltrating endometriosis compared with other women K van Kaam and team from the University of Maastricht set out to determine the frequencies of progesterone receptor gene polymorphisms in women with deep infiltrating endometriosis because alterations […]

Significant evidence of one or more susceptibility loci for endometriosis with near-Mendelian inheritance on chromosome 7p13-15
15 December 2006

December 2006 Research published in Human Reproduction by the collaborative International Endogene Study suggests that there may be one or more high-penetrance susceptibility loci for endometriosis with (near-)Mendelian inheritance. The collaborative International Endogene Study consists of two data sets (Oxford and Australia) comprising 1176 families with multiple affecteds. The aim of the research team was […]

Nutrition plays a role in reproductive health
15 December 2006

December 2006 At the 62nd Annual Meeting of the ASRM several new studies were highlighted for the impact nutrition has on the reproductive system Dian Shepperson Mills presented how nutritional therapy provides an effective method of improving fertility rates and reducing abdominal pain in women with endometriosis. She promotes an integrated medical approach to improve […]

Improved visualisation of endometriosis using a new spectral analysis autoflourescence laparoscopy system: a pilot study
15 November 2006

November 2006 First prize for technical achievement was awarded to Dr Steven Palter at the 62nd annual meeting of the ASRM for a new surgery technique that enables surgeons to see tumours and other pathologies invisible with previous methods. Illumination of certain tissues with specific light wavelengths results in autoflourescence of the tissue, which can […]

Endometriosis may be generated by mimicking the ontogenetic development of the female genital tract.
15 November 2006

November 2006 Researchers at Johann Wolfgang Goethe-University in Frankfurt, Germany, suggest that endometriosis can arise through metaplasia The team set out to compare the expression of genes playing a decisive role during the embryonic development of the female genital tract (WNT4, WNT5A, WNT7A, PAX8) in the peritoneum of patients with endometriosis and control patients. An […]

Effects of different stages of endometriosis on the outcome of in vitro fertilization
15 November 2006

November 2006 Researchers at McGill University in Montreal, Canada, suggest that the presence of endometriosis, including stages III and IV, does not affect IVF outcome. This study was retrospective, with matched case-controls, set in an academic tertiary referral centre. The study group consisted of 87 women with laparoscopically diagnosed endometriosis, and the control group consisted […]

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