Research and treatments

Latest news on clinical and scientific research in endometriosis.


Cycling and early pregnant endometrium as a site of regulated expression of the Vitamin D system
26 July 2007

Vitamin D is a major regulator of calcium and phosphate homeostasis but its most potent metabolite has been demonstrated to affect a wide range of functions including anti-proliferative and immunomodulatory effects.

Medical botanicals may have anti-inflammatory and pain-alleviating properties
19 July 2007

19 July 2007 Experimental evidence is accumulating to suggest that medicinal botanicals have anti-inflammatory and pain-alleviating properties and hold promise for treatment of endometriosis. The authors of this systematic review of clinical and experimental data on the use of medicinal herbs in the treatment of endometriosis suggest that medical botanicals may have anti-inflammatory and pain-alleviating […]

New approaches to endometriosis treatment – mouse experiments point the way
3 July 2007

3 JULY 2007 Two new experimental studies were presented at the 23rd meeting of ESHRE. Both use mouse models to target angiogenesis, which may play a role in endometriosis and thus provide novel potential treatments of the disease. Possible new directions for the treatment of endometriosis, were outlined in the presentation of two experimental studies […]

Endometriosis may increase the risk of certain cancers, but absolute risk remains low
2 July 2007

2 JULY 2007 Epidemiological studies presented at the 23rd annual meeting of ESHRE showed a headline grabbing increased cancer risk among women with endometriosis. But clinicians remind women with endometriosis that in fact this research is reassuring in that there appears to be no overall increased risk of cancer. According to Swedish researchers endometriosis is […]

A fresh look at three chemical mediators in endometriosis
19 June 2007

June 2007 Cytokines in the peritoneum, progesterone resistance, chemokines in the epithelium. What a cocktail. But each of these three chemical mediators may have a significant role to play in endometriosis. Cytokines in the Peritoneum Bedaiwy et al [1] recently investigated the concentrations of the interleukins IL-1 beta, IL-6, IL-8, IL-3 and tumor necrosis factor alpha […]

Cost of endometriosis higher than for Crohn’s and migraine
15 June 2007

June 2007 A systematic review of estimates and methodology of studies quantifying the costs of endometriosis concludes that costs are considerably higher than those related to Crohn’s disease or to migraine. The authors, who published their study in Human Reproduction in July 2007 [1], included studies of cost-of-illness analyses quantifying the economic impact of endometriosis […]

Prostaglandins and COX-2
15 June 2007

Focus on the increased role of prostaglandins and COX-2 in endometriosis suggest a new class of drugs may be considered in reducing the presence of prostaglandins in women with endometriosis

Review of effectiveness of LUNA and PSN in endometriosis surgery
31 May 2007

31 May 2007 Systematic review of laparoscopic uterosacral nerve ablation (LUNA) and presacral neurectomy (PSN) shows the evidence for nerve interruption in the management of dysmenorrhea is limited A review lead by Latthe et al at the University of Birmingham, UK, aimed to compare the two main surgical procedures available designed to cut sensory nerves […]

Statins show promise for relief of endometriosis
5 March 2007

5 March 2007 Canadian study shows that women suffering from endometriosis may benefit from statin treatment due to its inhibitory effect on angiogenesis. Robert Casper and his team, from the Toronto Centre for Advanced Reproductive Technology, set out to investigate the inhibitory effect of a statin on angiogenesis in a three-dimensional (3-D) culture of human […]

Diagnostic delay in endometriosis is confirmed – but why?
15 February 2007

Karen Ballard’s study describes women’s experiences of reaching a diagnosis of endometriosis. The authors call for more awareness of endometriosis to reduce an 8.5 year diagnostic delay.

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